Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411 | 0.95 | — | — | |
| SCHEMBL887973 | 0.95 | — | — | |
| SCHEMBL5760792 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL170117 | 0.90 | — | — | |
| Water SCHEMBL8082748 | 0.90 | — | — | |
| SCHEMBL15013516 | 0.90 | — | — | |
| Phosphine SCHEMBL5862962 | 0.90 | — | — | |
| SCHEMBL2357677 | 0.90 | — | — | |
| Iodide SCHEMBL20502819 | 0.90 | — | — | |
| SCHEMBL1486799 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113368115-B | Rocuronium bromide pharmaceutical composition and rocuronium bromide refining method | 上海药坦药物研究开发有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-113368115-A | Rocuronium bromide pharmaceutical composition and rocuronium bromide refining method | 上海药坦药物研究开发有限公司 | 2021-09-10 | — | — | CN | disclosed |
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |
| EP-1863753-B1 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | UNIV SOUTHERN CALIFORNIA (US) | 2017-09-20 | — | — | EP | disclosed |
| CN-107126660-A | A kind of composition for including fluorinated ketones contained | 中化蓝天集团有限公司 | 2017-09-05 | — | — | CN | disclosed |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
| EP-2022775-B1 | Trihydroxy polyunsaturated eicosanoids | UNIV SOUTHERN CALIFORNIA (US) | 2014-10-15 | — | — | EP | disclosed |
| CN-101405244-B | Optoelectronic component having a multilayer structure | GEN ELECTRIC | 2014-09-24 | — | — | CN | disclosed |
| US-8802874-B2 | Trihydroxy polyunsaturated eicosanoid derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130296590-A1 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | NATIONAL INSTITUTES OF HEALTH | 2013-11-07 | — | — | US | disclosed |
| CN-101405245-A | Optoelectronic component having a multilayer structure | GEN ELECTRIC (US) | 2009-04-08 | — | — | CN | disclosed |
| EP-2022775-A2 | Trihydroxy polyunsaturated eicosanoids | University of Southern California (US) | 2009-02-11 | — | — | EP | disclosed |
| EP-1863753-A2 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006105058-A2 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1528909-A4 | TRIHYDROXY POLYUNSATURATED EICOSANOIDS | UNIV SOUTHERN CALIFORNIA (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20050228047-A1 | Trihydroxy polyunsaturated eicosanoid derivatives | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | disclosed |
| US-6949664-B2 | Trihydroxy polyunsaturated eicosanoids | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-09-27 | — | — | US | disclosed |
| EP-1528909-A1 | TRIHYDROXY POLYUNSATURATED EICOSANOIDS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20030236423-A1 | Trihydroxy polyunsaturated eicosanoids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-25 | — | — | US | disclosed |
| WO-2003084305-A2 | TRIHYDROXY POLYUNSATURATED EICOSANOIDS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2003-10-16 | — | — | WO | disclosed |