Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isocupressic Acid SCHEMBL19139984 | 0.93 | POLB (0.66) | POLBMAPTPTPN1TAS2R31PNLIP | |
| Isocupressic Acid SCHEMBL13532265 | 0.93 | POLB (0.66) | POLBMAPTPTPN1TAS2R31PNLIP | |
| Agathic Acid SCHEMBL29358171 | 0.88 | TAS2R31 (0.64) | POLBMAPTPTPN1TAS2R31PNLIP | |
| Agathic Acid SCHEMBL30436331 | 0.88 | TAS2R31 (0.64) | POLBMAPTPTPN1TAS2R31PNLIP | |
| Agathic Acid SCHEMBL21914839 | 0.88 | TAS2R31 (0.64) | POLBMAPTPTPN1TAS2R31PNLIP | |
| SCHEMBL30436964 | 0.85 | POLB (0.58) | POLBMAPTPTPN1TAS2R31PNLIP | |
| SCHEMBL30671350 | 0.83 | POLB (0.67) | POLBMAPTPTPN1TAS2R31PNLIP | |
| SCHEMBL16622815 | 0.81 | PTPN1 (0.66) | POLBMAPTPTPN1TAS2R31PNLIP | |
| SCHEMBL16622825 | 0.81 | PTPN1 (0.66) | POLBMAPTPTPN1PNLIPPTPN2 | |
| SCHEMBL16622816 | 0.81 | POLB (0.81) | POLBMAPTPTPN1PNLIPPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |