Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27423329 | 0.83 | ADORA1 (0.46) | MEN1KMT2AADORA2AKDM4EALDH1A1 | |
| SCHEMBL1905542 | 0.83 | ADORA1 (0.46) | NPSR1MEN1KMT2AADORA2AKDM4E | |
| SCHEMBL3783457 | 0.83 | KDM4E (0.48) | NPSR1MEN1KMT2AADORA2AKDM4E | |
| SCHEMBL6236169 | 0.82 | ADORA1 (0.47) | NPSR1MEN1KMT2AGRM5ADORA2A | |
| SCHEMBL18269174 | 0.79 | ADORA1 (0.35) | NPSR1MEN1KMT2AGRM5ADORA2A | |
| SCHEMBL22283897 | 0.79 | ADORA1 (0.51) | NPSR1MEN1KMT2AADORA2AKDM4E | |
| SCHEMBL10226576 | 0.79 | CYP2A6 (0.42) | NPSR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4482253 | 0.76 | IKBKB (0.47) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL2618362 | 0.76 | MEN1 (0.44) | NPSR1MEN1KMT2AGRM5ADORA2A | |
| SCHEMBL7026138 | 0.72 | AS3MT (0.54) | MAPTPIM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518970-B2 | Compounds and methods of use | ABBVIE INC. (US) | 2013-08-27 | — | — | US | disclosed |