Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 3/20 | 0.32 |
| ▸ | GIPR | P48546 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962072 | 1.00 | MTTP (0.32) | MTTPPLGPLAUPLATGCGR | |
| SCHEMBL12581522 | 0.96 | MCHR1 (0.31) | MTTPMCHR1P2RY14OPRM1OPRK1 | |
| SCHEMBL1964078 | 0.96 | MCHR1 (0.31) | MTTPMCHR1P2RY14OPRM1OPRK1 | |
| SCHEMBL12553408 | 0.95 | MGAT2 (0.34) | MGAT2DGAT1MAPK14MEN1RAB9A | |
| SCHEMBL9973011 | 0.95 | PLG (0.32) | PLGPLAUPLATGCGRGIPR | |
| SCHEMBL1964161 | 0.95 | PLG (0.32) | PLGPLAUPLATGCGRGIPR | |
| SCHEMBL15214841 | 0.95 | RAF1 (0.36) | MTTPMAPK14MEN1KMT2A | |
| SCHEMBL1961362 | 0.94 | SMO (0.33) | MTTPGCGRGIPRMGAT2MCHR1 | |
| SCHEMBL9972773 | 0.94 | SMO (0.33) | MTTPGCGRGIPRMGAT2MCHR1 | |
| SCHEMBL12553415 | 0.93 | RAF1 (0.31) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045971-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2652553-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-04-06 | — | — | EP | disclosed |
| US-8518546-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |