Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874479 | 0.89 | MAPT (0.70) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL29475972 | 0.89 | MAPT (0.70) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL28874451 | 0.84 | MAPT (0.58) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL28874415 | 0.84 | MAPT (0.58) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL28874557 | 0.84 | MAPT (0.55) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL29878639 | 0.84 | MAPT (0.58) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL2246099 | 0.84 | MAPT (0.61) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL29032759 | 0.83 | MAPT (0.64) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL29878596 | 0.82 | MAPT (0.55) | MAPTNPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL28874322 | 0.82 | MAPT (0.55) | MAPTNPSR1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518980-B2 | Treatment of Duchenne muscular dystrophy | SUMMIT CORPORATION PLC (GB) | 2013-08-27 | — | — | US | disclosed |