⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15217528 | 0.96 | — | — | |
| SCHEMBL15217511 | 0.93 | — | — | |
| SCHEMBL15217523 | 0.90 | — | — | |
| SCHEMBL15219142 | 0.90 | — | — | |
| SCHEMBL15217216 | 0.87 | — | — | |
| SCHEMBL15217129 | 0.87 | — | — | |
| SCHEMBL15217168 | 0.87 | — | — | |
| SCHEMBL15108753 | 0.87 | — | — | |
| SCHEMBL15108663 | 0.87 | — | — | |
| SCHEMBL471016 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822448-B2 | Pyrazoloquinoline compound | ASTELLAS PHARMA INC. (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20130225553-A1 | PYRAZOLOQUINOLINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-08-29 | — | — | US | disclosed |