Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77913 | 0.88 | PARP1 (0.73) | PARP1AR | |
| SCHEMBL30416453 | 0.88 | PARP1 (0.73) | PARP1AR | |
| SCHEMBL15908002 | 0.84 | PARP1 (0.69) | PARP1 | |
| SCHEMBL12955358 | 0.84 | PARP1 (0.72) | PARP1AR | |
| SCHEMBL12955528 | 0.82 | PARP1 (0.72) | PARP1AR | |
| SCHEMBL3387433 | 0.81 | PARP1 (0.70) | PARP1AR | |
| SCHEMBL1028195 | 0.81 | PARP1 (0.72) | PARP1AR | |
| SCHEMBL1824686 | 0.80 | PARP1 (0.86) | PARP1 | |
| SCHEMBL13265557 | 0.80 | PARP1 (0.76) | PARP1AR | |
| SCHEMBL1689488 | 0.79 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994104-A | Compound serving as PARP-NAMPT double-target inhibitor and application thereof | 天津市医药科学研究所(天津市医药与健康研究中心) | 2024-11-22 | — | — | CN | claimed |
| CN-110845425-B | Phthalazine derivative and preparation method and application thereof | 合肥工业大学 | 2023-09-08 | — | — | CN | claimed |
| US-20250270212-A1 | CHIMERIC COMPOUNDS USEFUL IN TREATING DISEASES | PADARN THERAPEUTICS INC (US) | 2025-08-28 | — | — | US | disclosed |
| CN-118994104-A | Compound serving as PARP-NAMPT double-target inhibitor and application thereof | 天津市医药科学研究所(天津市医药与健康研究中心) | 2024-11-22 | — | — | CN | disclosed |
| CN-115872976-B | Quinoline derivative, pharmaceutical composition containing quinoline derivative and application of pharmaceutical composition | 中国药科大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-110845425-B | Phthalazine derivative and preparation method and application thereof | 合肥工业大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-115872976-A | Quinoline derivative, pharmaceutical composition containing quinoline derivative and application of quinoline derivative | 中国药科大学 | 2023-03-31 | — | — | CN | disclosed |
| US-8999985-B2 | Substituted phthalazin-1(2H)-ones, preparation processes and medical uses thereof | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2015-04-07 | — | — | US | disclosed |
| US-20130224107-A1 | HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224107-A1 | HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | PARP1, PARP3, PARP2 | PARP1 1/4885AR 1430/4885 |
| US-20250270212-A1 | CHIMERIC COMPOUNDS USEFUL IN TREATING DISEASES | WEE1, WEE2, PARP1 | PARP1 3/4885AR 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.