⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2621400 | 1.00 | — | — | |
| SCHEMBL91627 | 1.00 | — | — | |
| SCHEMBL12290470 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL84191 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL26982939 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL30604217 | 0.96 | — | — | |
| SCHEMBL25142120 | 0.84 | — | — | |
| SCHEMBL13307057 | 0.84 | — | — | |
| SCHEMBL8253648 | 0.84 | — | — | |
| SCHEMBL12569227 | 0.84 | FUCA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220242859-A1 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. | 2022-08-04 | — | — | US | disclosed |
| US-20180037893-A1 | NOVEL LOW MOLECULAR WEIGHT CYCLIC AMINE CONTAINING CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2018-02-08 | — | — | US | disclosed |
| US-9796977-B2 | Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9725442-B2 | Heterocyclic derivative having PGD2 receptor antagonist activity | SHIONOGI & CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |
| US-20150361434-A1 | NOVEL LOW MOLECULAR WEIGHT CYCLIC AMINE CONTAINING CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2015-12-17 | — | — | US | disclosed |
| US-9187460-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-9067882-B2 | Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20140364427-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS, INC. | 2014-12-11 | — | — | US | disclosed |
| US-20140275074-A1 | HETEROCYCLIC DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20130225836-A1 | NOVEL LOW MOLECULAR WEIGHT CYCLIC AMINE CONTAINING CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2013-08-29 | — | — | US | disclosed |