⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503471 | 0.77 | — | — | |
| SCHEMBL15886147 | 0.77 | — | — | |
| SCHEMBL7864033 | 0.74 | — | — | |
| SCHEMBL18414549 | 0.74 | — | — | |
| SCHEMBL15141638 | 0.74 | — | — | |
| SCHEMBL101393 | 0.74 | — | — | |
| SCHEMBL15142570 | 0.74 | — | — | |
| SCHEMBL11423545 | 0.74 | — | — | |
| SCHEMBL20836758 | 0.74 | — | — | |
| SCHEMBL12214929 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923082-A | 4-methoxyl-5-hydroxy canthinone ramification | UNIV CHINA PHARMA | 2014-07-16 | — | — | CN | claimed |
| CN-103097345-A | New process | HOFFMANN LA ROCHE | 2013-05-08 | — | — | CN | claimed |
| CN-101573319-B | Process for preparing 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid | HOFFMANN LA ROCHE | 2013-04-03 | — | — | CN | claimed |
| CN-102066311-A | 1-(2-ethyl-butyl) -cyclohexanecarboxylic acid ester as an intermediate in the preparation of pharmaceutically active amides | HOFFMANN LA ROCHE | 2011-05-18 | — | — | CN | claimed |
| CN-101981001-A | New process for the preparation of cyclohexanecarboxylic acid dericatives | HOFFMANN LA ROCHE | 2011-02-23 | — | — | CN | claimed |
| CN-101952236-A | New process for the preparation of cyclohexanecarboxylic acid derivatives via the corresponding cyclohexanecarboxamide derivative | HOFFMANN LA ROCHE | 2011-01-19 | — | — | CN | claimed |
| CN-101573319-A | Process for preparing 1- (2-ethyl-butyl) -cyclohexanecarboxylic acid | HOFFMANN LA ROCHE (CH) | 2009-11-04 | — | — | CN | claimed |
| EP-3012247-B1 | MANUFACTURING METHOD FOR 2-AMINO-2-HYDROXYIMINO-N-ALKOXY ACETOIMIDOYL CYANIDE, AND MANUFACTURING INTERMEDIATE THEREOF | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-01-10 | — | — | EP | disclosed |
| US-9453051-B2 | Cyclosporin derivatives | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-3012247-A2 | MANUFACTURING METHOD FOR 2-AMINO-2-HYDROXYIMINO-N-ALKOXY ACETOIMIDOYL CYANIDE, AND MANUFACTURING INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2016-04-27 | — | — | EP | disclosed |
| CN-105377812-A | Manufacturing method for 2-amino-2-hydroxyimino-n-alkoxy acetoimidoyl cyanide, and manufacturing intermediate thereof | IHARA CHEMICAL IND CO | 2016-03-02 | — | — | CN | disclosed |
| US-20140316104-A1 | CYCLOSPORIN DERIVATIVES | LEAD DISCOVER CENTER GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| CN-103923082-A | 4-methoxyl-5-hydroxy canthinone ramification | UNIV CHINA PHARMA | 2014-07-16 | — | — | CN | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1172809-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 1998-02-11 | — | — | CN | disclosed |
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |
| CN-1104622-A | Preparation of lignan analogues | SHIONOGI & CO (JP) | 1995-07-05 | — | — | CN | disclosed |
| CN-1096156-A | 5-replaces-2,4-diaminopyrimidine derivatives insecticide | FMC CORP (US) | 1994-12-14 | — | — | CN | disclosed |
| CN-1061963-A | Be used as the croak pyridine class of the 4-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-06-17 | — | — | CN | disclosed |