SCHEMBL15224764

SCHEMBL15224764

CC(C)CCC(c1ccc(OC#N)cc1)c1ccc(OC#N)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.35
PBRM1 Q86U86 1/20 0.34
KMT2A Q03164 5/20 0.33
HTT P42858 4/20 0.33
ALDH1A1 P00352 4/20 0.33
MITF O75030 4/20 0.33
MEN1 O00255 4/20 0.33
MAPK1 P28482 2/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
GPR35 Q9HC97 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
XBP1 P17861 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15224837 0.90 RARB (0.34) CYP19A1PBRM1KMT2AHTTALDH1A1
SCHEMBL15225008 0.85 FFAR1 (0.38) CYP19A1PBRM1KMT2AHTTALDH1A1
SCHEMBL15224809 0.84 KMT2A (0.44) PBRM1KMT2AHTTALDH1A1MITF
SCHEMBL15224703 0.84 PBRM1 (0.35) CYP19A1PBRM1ALDH1A1GAASMN1; SMN2
SCHEMBL3421152 0.84 CYP19A1 (0.35) CYP19A1PBRM1KMT2AHTTALDH1A1
SCHEMBL15224501 0.81 SLC2A1 (0.39) CYP19A1PBRM1LMNA
SCHEMBL5072879 0.79 CYP17A1 (0.45) CYP19A1PBRM1ALDH1A1GAASMN1; SMN2
SCHEMBL15224529 0.79 SLC2A1 (0.42) CYP19A1PBRM1ALDH1A1LMNA
SCHEMBL17042736 0.79 CYP19A1 (0.37) CYP19A1KMT2AHTTMITFMEN1
SCHEMBL15225006 0.78 SLC2A1 (0.44) HTTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US claimed
US-9453126-B2 Cyanate ester compound, curable resin composition containing cyanate ester compound, and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-27 US disclosed
US-20140242394-A1 CURABLE RESIN COMPOSITION AND METHOD FOR MANUFACTURING CURED PRODUCT USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-28 US disclosed
EP-2733159-A1 CURABLE RESIN COMPOSITION AND PROCESS FOR PRODUCING CURED PRODUCTS USING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2014-05-21 EP disclosed
US-20130281640-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-10-24 US disclosed
EP-2634205-A1 CYANATE ESTER COMPOUND, CURABLE RESIN COMPOSITION CONTAINING CYANATE ESTER COMPOUND, AND CURED PRODUCT THEREOF Mitsubishi Gas Chemical Company, Inc. (JP) 2013-09-04 EP disclosed