Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402078 | 1.00 | AURKA (0.46) | AURKAAURKB | |
| SCHEMBL4124966 | 0.90 | AURKA (0.48) | AURKAAURKB | |
| SCHEMBL3535817 | 0.89 | AURKA (0.51) | AURKAAURKB | |
| SCHEMBL401815 | 0.80 | AURKA (0.46) | AURKAAURKB | |
| SCHEMBL400511 | 0.80 | AURKA (0.38) | AURKAAURKB | |
| SCHEMBL10172360 | 0.80 | AURKA (0.38) | AURKAAURKB | |
| SCHEMBL3526824 | 0.79 | AURKA (0.40) | AURKAAURKB | |
| SCHEMBL401566 | 0.77 | PDE2A (0.37) | AURKAAURKB | |
| SCHEMBL10172355 | 0.77 | PDE2A (0.37) | AURKAAURKB | |
| SCHEMBL399614 | 0.77 | AURKA (0.47) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017279-B1 | AMINOPYRIMIDINE DERIVATIVES HAVING AURORA-A-SELECTIVE INHIBITORY ACTIVITY | MSD KK (JP) | 2013-09-04 | — | — | EP | disclosed |