SCHEMBL15225699

SCHEMBL15225699

O=C(NCCCC1CC1)Oc1nnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)s1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 15/20 0.64
DCTPP1 Q9H773 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15225478 0.95 SCD (0.63) SCDDCTPP1
SCHEMBL15225581 0.91 SCD (0.59) SCDDCTPP1
SCHEMBL15225104 0.90 SCD (0.63) SCDDCTPP1
SCHEMBL15224968 0.89 SCD (0.63) SCDDCTPP1
SCHEMBL15225413 0.89 SCD (0.63) SCDDCTPP1
SCHEMBL15225356 0.89 SCD (0.63) SCDDCTPP1
SCHEMBL15225358 0.88 SCD (0.57) SCD
SCHEMBL15225094 0.87 SCD (0.51) SCDDCTPP1
SCHEMBL15225330 0.86 SCD (0.63) SCDDCTPP1
SCHEMBL24230 0.86 SCD (0.71) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830837-B1 HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY STEAROYL-COA DESATURASE ENZYMES XENON PHARMACEUTICALS INC (CA) 2013-09-04 EP claimed