Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306500 | 0.86 | ERN1 (0.47) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL4041509 | 0.84 | ERN1 (0.56) | ERN1CA1CA2TUBB4ATUBB | |
| SCHEMBL4036525 | 0.77 | ERN1 (0.55) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL15226080 | 0.71 | ERN1 (0.52) | ERN1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL4040519 | 0.71 | ERN1 (0.47) | ERN1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12767808 | 0.70 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12767867 | 0.70 | ERN1 (1.00) | ERN1 | |
| SCHEMBL15009764 | 0.70 | ERN1 (0.77) | ERN1PRKDC | |
| SCHEMBL19475454 | 0.69 | ERN1 (0.50) | ERN1MAPTALDH1A1POLBTUBB4A | |
| SCHEMBL4043040 | 0.69 | ERN1 (0.49) | ERN1MAPTKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |