Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15225050 | 0.86 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL15338545 | 0.86 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL6918319 | 0.86 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL6917593 | 0.86 | BACE1 (0.58) | BACE1BACE2 | |
| SCHEMBL15241666 | 0.85 | BACE1 (0.78) | BACE1BACE2 | |
| SCHEMBL15241667 | 0.80 | BACE1 (0.41) | BACE1BACE2 | |
| Elenbecestat SCHEMBL29359992 | 0.80 | BACE1 (1.00) | BACE1BACE2 | |
| Elenbecestat SCHEMBL2620149 | 0.80 | BACE1 (1.00) | BACE1BACE2 | |
| Elenbecestat SCHEMBL2933223 | 0.80 | BACE1 (1.00) | BACE1BACE2 | |
| Elenbecestat SCHEMBL30477102 | 0.80 | BACE1 (1.00) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456774-B1 | FUSED AMINODIHYDRO-OXAZINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |