Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TK1 | P04183 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thymidine Monophosphate SCHEMBL16323213 | 0.99 | TYMS (0.75) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL3984895 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL18785041 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL16280929 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL7876022 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL21257 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL2037921 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL16092807 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL8366987 | 0.94 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL29463974 | 0.94 | POLB (0.80) | TYMSPOLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013142831-A1 | METHODS OF MAKING AND USING THIOXOTHIAZOLIDINE AND RHODANINE DERIVATIVES AS HIV-1 AND JSP-1 INHIBITORS | SOUTHERN METHODIST UNIVERSITY (US) | 2013-09-26 | — | — | WO | disclosed |