Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660078 | 0.92 | USP30 (0.49) | USP30FFAR1NR1H2DDB1CRBN | |
| SCHEMBL25236223 | 0.88 | USP30 (0.45) | USP30FFAR1NR1H2DDB1CRBN | |
| SCHEMBL15273426 | 0.88 | USP30 (0.45) | USP30FFAR1NR1H2DDB1CRBN | |
| SCHEMBL15272934 | 0.87 | USP30 (0.45) | USP30FFAR1NR1H2DDB1CRBN | |
| SCHEMBL2423601 | 0.86 | USP30 (0.55) | USP30FFAR1DDB1CRBNGPR119 | |
| SCHEMBL2422530 | 0.86 | USP30 (0.55) | USP30FFAR1DDB1CRBNGPR119 | |
| SCHEMBL2422527 | 0.86 | USP30 (0.55) | USP30FFAR1DDB1CRBNGPR119 | |
| SCHEMBL320828 | 0.85 | USP30 (0.52) | USP30FFAR1DDB1CRBNGPR119 | |
| SCHEMBL659798 | 0.84 | CHRM2 (0.44) | USP30FFAR1DDB1CRBNGPR119 | |
| SCHEMBL29548160 | 0.84 | CHRM2 (0.44) | USP30FFAR1DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013138210-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE | XI NING (US) | 2013-09-19 | — | — | WO | disclosed |