Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 11/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768865 | 1.00 | CSNK2B (0.50) | CSNK2BTYK2STAT3GRM2CDK1 | |
| SCHEMBL1527970 | 0.90 | CSNK2B (0.53) | CSNK2BTYK2STAT3PDE4DMEN1 | |
| SCHEMBL1527969 | 0.90 | CSNK2B (0.53) | CSNK2BTYK2STAT3PDE4DMEN1 | |
| SCHEMBL12830240 | 0.87 | CSNK2B (0.49) | CSNK2BTYK2STAT3P2RX7MEN1 | |
| SCHEMBL1527860 | 0.87 | CSNK2B (0.50) | CSNK2BTYK2STAT3CDK1CCNE1 | |
| SCHEMBL12769153 | 0.87 | CSNK2B (0.50) | CSNK2BTYK2STAT3GRM2P2RX7 | |
| SCHEMBL12768845 | 0.87 | CSNK2B (0.50) | CSNK2BTYK2STAT3CDK1CCNE1 | |
| SCHEMBL12841429 | 0.85 | CSNK2B (0.47) | CSNK2BTYK2CDK1CCNE1CDK2 | |
| SCHEMBL1527901 | 0.84 | CSNK2B (0.60) | CSNK2BTYK2CDK1CCNE1CDK2 | |
| SCHEMBL12768852 | 0.84 | CSNK2B (0.60) | CSNK2BTYK2CDK1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071115-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071115-A1 | PHARMACEUTICALLY USEFUL HETEROCYCLE-SUBSTITUTED LACTAMS | PIM2, PIM1, PIM3 | CSNK2B 17/4885TYK2 39/4885STAT3 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.