SCHEMBL15310012

SCHEMBL15310012

Cc1cc(-c2nc3cnc(Sc4nccs4)nc3o2)cc(C)c1OCC(=O)N1CCC[C@@H]1OC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.38
CPT2 P23786 2/20 0.31
CPT1A P50416 2/20 0.31
CPT1B Q92523 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15310121 0.91 S1PR1 (0.39) S1PR1CPT2CPT1ACPT1B
SCHEMBL14796973 0.83 S1PR1 (0.52) S1PR1
SCHEMBL15309983 0.78 S1PR1 (0.51) S1PR1CPT2CPT1ACPT1B
SCHEMBL2224649 0.77 S1PR1 (0.51) S1PR1CPT2CPT1A
SCHEMBL15310217 0.76 S1PR1 (0.59) S1PR1CPT2CPT1ACPT1B
SCHEMBL15310194 0.76 S1PR1 (0.71) S1PR1CPT2CPT1A
SCHEMBL2224195 0.73 S1PR1 (0.33) S1PR1
SCHEMBL14797142 0.73 S1PR1 (0.53) S1PR1
SCHEMBL15309981 0.70 S1PR1 (0.52) S1PR1CPT2CPT1ACPT1B
SCHEMBL2223289 0.69 S1PR1 (0.42) S1PR1CPT2CPT1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231327-B1 CATALYST COMPOSITION INCLUDING ZIRCONIUM COMPOUNDS FOR ESTERFICATION REACTION AND METHOD FOR PREPARING ESTER COMPOUNDS LG CHEMICAL LTD (KR) 2013-10-16 EP claimed