Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310002 | 0.96 | S1PR1 (0.52) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310052 | 0.94 | S1PR1 (0.53) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310137 | 0.91 | S1PR1 (0.53) | S1PR1HPGDLMNAPOLBMAPT | |
| SCHEMBL15309990 | 0.90 | S1PR1 (0.48) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310032 | 0.90 | S1PR1 (0.51) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310159 | 0.89 | S1PR1 (0.53) | S1PR1LMNAPOLBMAPTCETP | |
| SCHEMBL15310001 | 0.88 | S1PR1 (0.53) | S1PR1HPGDLMNAPOLBFKBP1A | |
| SCHEMBL2224649 | 0.88 | S1PR1 (0.51) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310232 | 0.87 | S1PR1 (0.49) | S1PR1HPGDLMNAPOLBGRIN2B | |
| SCHEMBL15310183 | 0.87 | S1PR1 (0.70) | S1PR1LMNAPOLBFKBP1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523960-B1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-10-16 | — | — | EP | disclosed |