Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15310306 | 1.00 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL586271 | 1.00 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL585703 | 1.00 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL586385 | 0.94 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL600926 | 0.92 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL604577 | 0.92 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL602359 | 0.90 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL601380 | 0.88 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL586207 | 0.84 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL1607074 | 0.83 | KCNH2 (0.67) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417141-B1 | 2-HYDROXYETHYL-1H-QUINOLIN-2-ONE DERIVATIVES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ACTELION PHARMACEUTICALS LTD (CH) | 2013-10-16 | — | — | EP | disclosed |