Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949085 | 1.00 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL11888797 | 0.95 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL11888798 | 0.95 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL11949091 | 0.88 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4421912 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL4421903 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL2131534 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL27870802 | 0.86 | S1PR1 (0.47) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL11888760 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL11888761 | 0.86 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058317-B1 | AMINOPHOSPHORIC ACID ESTER DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2013-10-16 | — | — | EP | disclosed |