Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949089 | 1.00 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4SIRT2 | |
| SCHEMBL11888754 | 0.90 | S1PR1 (0.54) | S1PR1S1PR3S1PR5S1PR4SIRT2 | |
| SCHEMBL11888753 | 0.90 | S1PR1 (0.54) | S1PR1S1PR3S1PR5S1PR4SIRT2 | |
| SCHEMBL4339103 | 0.87 | S1PR1 (0.37) | S1PR1S1PR3SIRT2SLC6A2SLC6A4 | |
| SCHEMBL4339109 | 0.87 | S1PR1 (0.37) | S1PR1S1PR3SIRT2SLC6A2SLC6A4 | |
| SCHEMBL11888760 | 0.85 | S1PR1 (0.56) | S1PR1S1PR3S1PR5S1PR4SIRT2 | |
| SCHEMBL11888761 | 0.85 | S1PR1 (0.56) | S1PR1S1PR3S1PR5S1PR4SIRT2 | |
| SCHEMBL4339107 | 0.85 | SLC6A2 (0.36) | S1PR1S1PR3SIRT2SLC6A2SLC6A4 | |
| SCHEMBL3300524 | 0.84 | SLC6A2 (0.40) | S1PR1S1PR3SIRT2SLC6A2SLC6A4 | |
| SCHEMBL3300531 | 0.84 | SLC6A2 (0.40) | S1PR1S1PR3SIRT2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058317-B1 | AMINOPHOSPHORIC ACID ESTER DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN SEIYAKU KK (JP) | 2013-10-16 | — | — | EP | disclosed |