Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.51 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732112 | 0.92 | TRPV1 (0.59) | TRPV1KITEPHX2TRPM8 | |
| SCHEMBL5392806 | 0.85 | TRPV1 (0.67) | TRPV1EPHX2TRPM8 | |
| SCHEMBL30753827 | 0.83 | TRPV1 (0.57) | TRPV1PANK3EPHX2TRPM8 | |
| SCHEMBL5461207 | 0.83 | TRPV1 (0.57) | TRPV1PANK3EPHX2TRPM8 | |
| SCHEMBL31679061 | 0.81 | TRPV1 (0.66) | TRPV1EPHX2 | |
| SCHEMBL2725222 | 0.81 | TRPV1 (0.66) | TRPV1EPHX2 | |
| SCHEMBL10307946 | 0.79 | TRPV1 (0.77) | TRPV1EPHX2TRPM8 | |
| SCHEMBL2723773 | 0.74 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL2724621 | 0.73 | TRPV1 (0.62) | TRPV1MAPTKDM4ETRPM8 | |
| SCHEMBL30753826 | 0.72 | TRPV1 (0.67) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192508-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIV HAWAII (US) | 2019-06-27 | — | — | US | disclosed |
| US-10137123-B2 | Methods and compositions for prevention and treatment of cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2018-11-27 | — | — | US | disclosed |
| US-20170231982-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII | 2017-08-17 | — | — | US | disclosed |
| US-9084786-B2 | Methods and compositions for prevention and treatmentof cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2015-07-21 | — | — | US | disclosed |
| US-20130274271-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENTOF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII (US) | 2013-10-17 | — | — | US | disclosed |