Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945405 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL2952790 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL1400171 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL2942293 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL154515 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL153580 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL2944805 | 1.00 | MAPT (0.61) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL1527806 | 0.98 | MAPT (0.58) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL8669549 | 0.97 | MAPT (0.57) | MAPTRXFP1TSHRKCNH2FAAH | |
| SCHEMBL135651 | 0.93 | TSHR (0.59) | MAPTRXFP1TSHRKCNH2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623996-B2 | Cold active enzyme and method thereof | UNIVERSITY PUTRA MALAYSIA (MY) | 2014-01-07 | — | — | US | claimed |
| US-20120058514-A1 | COLD ACTIVE ENZYME AND METHOD THEREOF | UNIVERSITY PUTRA MALAYSIA (MY) | 2012-03-08 | — | — | US | claimed |
| CN-118272342-A | Lipase LUCA based on ancestral sequence reconstruction and application thereof | 山东师范大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-115838704-A | Lipase mutant and application thereof | 中国海洋大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-115040572-B | Natural composition for promoting oil discharge and reducing weight and preparation method thereof | 陕西海斯夫生物工程有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113846074-B | Thermomyces lanuginosus lipase mutant G91C and application thereof | 南京林业大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-112352021-B | Biodegradable resin molded article, process for producing the same, and pellet used therein | 株式会社TBM | 2022-06-03 | — | — | CN | disclosed |
| CN-113684195-A | Sterol esterase and coding gene and mutant thereof | 中国海洋大学 | 2021-11-23 | — | — | CN | disclosed |
| EP-3341458-B1 | DETERGENT COMPOSITIONS WITH LIPASE AND BIOSURFACTANT | UNILEVER IP HOLDINGS B V (NL) | 2021-10-20 | — | — | EP | disclosed |
| CN-113166749-A | Printable magnetic powder for immobilizing biological nano catalyst and 3D printed object | 齐姆特罗尼克斯催化系统股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112352021-A | Biodegradable resin molded article, process for producing the same, and pellet used therein | 株式会社TBM | 2021-02-09 | — | — | CN | disclosed |
| EP-0426656-A2 | Process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1991-05-08 | — | — | EP | disclosed |
| WO-1991003563-A1 | METHOD OF PREPARATION OF MONOGLYCERIDES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-21 | — | — | WO | disclosed |
| US-4933287-A | FROM PSEUDOMONAS PSEUDOALCALIGENES OR STUTZERI | GIST-BROCADES N.V. (NL) | 1990-06-12 | — | — | US | disclosed |
| US-4886750-A | STEREOSELECTIVE HYDROLYSIS USING MICROORGANISMS | GIST-BROCADES N.V. (NL) | 1989-12-12 | — | — | US | disclosed |
| EP-0191217-B1 | PROCESS FOR PRODUCING GLYCERIDES IN THE PRESENCE OF LIPASES | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-03-16 | — | — | EP | disclosed |
| EP-0233656-A1 | Microbial esterase and process for the preparation of 2-arylpropionic acids | GIST-BROCADES N.V. (NL) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987000859-A1 | NOVEL LIPOLYTIC ENZYMES AND THEIR USE IN DETERGENT COMPOSITIONS | GIST-BROCADES N.V. (NL) | 1987-02-12 | — | — | WO | disclosed |
| EP-0191217-A1 | Process for producing glycerides in the presence of lipases | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | disclosed |