Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.78 |
| ▸ | FNTB | P49356 | 16/20 | 0.78 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552462 | 0.93 | FNTA (0.91) | FNTAFNTBPGGT1BCYP3A4 | |
| Water SCHEMBL3974460 | 0.92 | FNTA (0.89) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL1683559 | 0.87 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3558679 | 0.82 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5022612 | 0.81 | FNTA (0.82) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL3553255 | 0.81 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL14588534 | 0.81 | FNTA (0.80) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5023321 | 0.80 | FNTA (0.79) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL14588533 | 0.79 | FNTA (0.77) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL5022671 | 0.78 | FNTA (0.77) | FNTAFNTBPGGT1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557847-B2 | Synergistic modulation of FLT3 kinase using a FLT3 inhibitor and a farnesyl transferase inhibitor | JANSSEN PHARMACEUTICA, N.V. (BE) | 2013-10-15 | — | — | US | disclosed |