Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.74 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10235309 | 0.90 | CCR4 (0.90) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL10235193 | 0.88 | CCR4 (0.84) | CCR4CCR5FFAR4SLCO1B1 | |
| Trifluoroacetic Acid SCHEMBL357216 | 0.85 | CCR4 (0.82) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL10279073 | 0.85 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL13186812 | 0.85 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| Formic Acid SCHEMBL359279 | 0.85 | CCR4 (0.79) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL10278712 | 0.85 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| Hydrochloric Acid SCHEMBL358595 | 0.84 | CCR4 (0.99) | CCR4CCR5FFAR4SLCO1B1 | |
| Trifluoroacetic Acid SCHEMBL357625 | 0.81 | CCR4 (0.91) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL15314731 | 0.79 | CCR4 (0.69) | CCR4CCR5FFAR4SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401270-B1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2013-10-16 | — | — | EP | disclosed |