Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888209 | 1.00 | PNP (0.85) | PNPMTAP | |
| SCHEMBL9888043 | 0.92 | PNP (1.00) | PNPMTAP | |
| SCHEMBL9888094 | 0.92 | PNP (1.00) | PNPMTAP | |
| SCHEMBL15315692 | 0.92 | PNP (1.00) | PNPMTAP | |
| SCHEMBL15315696 | 0.90 | PNP (0.89) | PNPMTAP | |
| SCHEMBL9888210 | 0.90 | PNP (0.89) | PNPMTAP | |
| SCHEMBL9888006 | 0.90 | PNP (1.00) | PNPMTAP | |
| SCHEMBL9888033 | 0.90 | PNP (1.00) | PNPMTAP | |
| SCHEMBL9888095 | 0.90 | PNP (1.00) | PNPMTAP | |
| SCHEMBL4736861 | 0.90 | PNP (1.00) | PNPMTAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290501-B2 | Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290501-B2 | Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130274220-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-10-17 | — | — | US | disclosed |
| US-20130274220-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274220-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | MTAP, MPG, MTMR1 | PNP 14/4885MTAP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.