Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30325478 | 0.84 | ATM (0.53) | ATMCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL20532613 | 0.84 | ATM (0.53) | ATMCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL28532312 | 0.84 | ATM (0.53) | ATMCHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL2494717 | 0.81 | ATM (0.53) | ATMCHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL2488710 | 0.81 | ATM (0.53) | ATMCHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL3962581 | 0.81 | ATM (0.53) | ATMCHRM2CHRM1CHRM3MEN1 | |
| SCHEMBL3963916 | 0.81 | ATM (0.53) | ATMCHRM2CHRM1CHRM3MEN1 | |
| Carbamic Acid SCHEMBL4770746 | 0.78 | ATM (0.50) | ATMCHRM3 | |
| SCHEMBL1365118 | 0.78 | ATM (0.73) | ATMCHRM2CHRM1CHRM3 | |
| SCHEMBL743699 | 0.78 | ATM (0.73) | ATMCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029043-A1 | HETEROARYL BTK INHIBITORS | BIOGEN IDEC MA INC. (US) | 2011-03-10 | — | — | WO | disclosed |