SCHEMBL15319669

SCHEMBL15319669

CC(C)(C)OC(=O)N1CC(F)(CO)C1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.45
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 1/20 0.37
EPHX2 P34913 1/20 0.37
CTSK P43235 1/20 0.36
RECQL P46063 1/20 0.36
EPHX1 P07099 1/20 0.36
RORC P51449 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21216177 0.87 USP2 (0.42) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL15715964 0.87 USP2 (0.42) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL19459465 0.87 USP2 (0.42) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL29491128 0.86 NR1H2 (0.43) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL20136928 0.86 USP2 (0.43) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL15335051 0.86 USP2 (0.43) NR1H2USP2SMN1; SMN2HPGDEPHX2
SCHEMBL27301567 0.85 NR1H2 (0.40) NR1H2USP2SMN1; SMN2RORCDDB1
SCHEMBL21216433 0.84 HPGD (0.41) NR1H2USP2SMN1; SMN2HPGDCTSK
SCHEMBL1976118 0.84 HPGD (0.41) NR1H2USP2SMN1; SMN2HPGDCTSK
SCHEMBL12179879 0.84 HPGD (0.41) NR1H2USP2SMN1; SMN2HPGDCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747234-A1 KV1.3 POTASSIUM CHANNEL ANTAGONISTS Muna Therapeutics ApS (DK) 2026-05-27 EP disclosed
EP-4747235-A1 KV1.3 POTASSIUM CHANNEL ANTAGONISTS Muna Therapeutics ApS (DK) 2026-05-27 EP disclosed
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECH LIMITED (GB) 2026-05-21 US disclosed
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-07 US disclosed
WO-2026090104-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-12590090-B2 Pyrimidine-and nitrogen-containing bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2026-03-31 US disclosed
EP-3806853-B1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES ONCO3R THERAPEUTICS BV (BE) 2026-03-18 EP disclosed
US-12559506-B2 Indazole based compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 EP disclosed
US-20260022109-A1 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2026-01-22 US disclosed
US-20150158861-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-06-11 US disclosed
US-20150158861-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-06-11 US disclosed
US-20150158861-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-06-11 US disclosed
EP-2855472-A1 NAPHTHYRIDINONE DERIVATIVES AS INHIBITORS OF CYTOMEGALOVIRUS DNA POLYMERASE Boehringer Ingelheim International GmbH (DE) 2015-04-08 EP disclosed
US-20150080366-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-03-19 US disclosed
US-20150080366-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-03-19 US disclosed
WO-2014078331-A1 N-(ARYLALKYL)-N'-PYRAZOLYL-UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2014-05-22 WO disclosed
WO-2013152063-A1 NAPHTHYRIDINONE DERIVATIVES AS INHIBITORS OF CYTOMEGALOVIRUS DNA POLYMERASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-10-10 WO disclosed
WO-2013152065-A2 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-10-10 WO disclosed
WO-2013152063-A1 NAPHTHYRIDINONE DERIVATIVES AS INHIBITORS OF CYTOMEGALOVIRUS DNA POLYMERASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER EGFR, KRAS, O60361 NR1H2 2747/4885USP2 4075/4885SMN1; SMN2 2548/4885
US-12559506-B2 Indazole based compounds and associated methods of use LRRK2, CRBN, CLK2 NR1H2 4332/4885USP2 100/4885SMN1; SMN2 1087/4885
US-20260124205-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNNA1, CTNND1 NR1H2 37/4885USP2 3589/4885SMN1; SMN2 2898/4885
US-20150158861-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS CCNT1, CDKN1A, FOXM1 NR1H2 1141/4885USP2 3876/4885SMN1; SMN2 2930/4885
US-20260022109-A1 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE CHEK1, CHEK2, WEE1 NR1H2 3731/4885USP2 2557/4885SMN1; SMN2 1388/4885
US-12590090-B2 Pyrimidine-and nitrogen-containing bicyclic compound IRAK1, IRAK4, IRAK2 NR1H2 508/4885USP2 3537/4885SMN1; SMN2 2936/4885
US-20150080366-A1 CYTOMEGALOVIRUS INHIBITOR COMPOUNDS CDKN1A, IFNAR1, CCNT1 NR1H2 1253/4885USP2 3975/4885SMN1; SMN2 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.