Deaminohydroxyvaline

SCHEMBL15323274

CC(=O)C(=O)O.CC(C)C(O)C(=O)O.CC(C)C(O)C(=O)O.CC(C)C(O)C(=O)O.CC(O)CC(=O)O.CC(O)CC(=O)O.CC(O)CC(=O)O.CCCC(O)C(=O)O.CCCC(O)C(=O)O.O=C(O)C1CCCN1.O=C(O)C1CCCN1.O=C(O)CCC(=O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Deaminohydroxyvaline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	DPP7	Q9UHL4	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Deaminohydroxyvaline SCHEMBL15323086	0.96	DPP7 (0.31)	DPP7
Deaminohydroxyvaline SCHEMBL15323082	0.96	DPP7 (0.31)	DPP7
Deaminohydroxyvaline SCHEMBL15322990	0.92	—	—
Proline SCHEMBL15323031	0.87	DPP7 (0.38)	DPP7
Deaminohydroxyvaline SCHEMBL15322989	0.83	DPP7 (0.38)	DPP7
Deaminohydroxyvaline SCHEMBL15322986	0.83	DPP7 (0.38)	DPP7
Succinic Acid SCHEMBL15322394	0.80	ACE (0.32)	DPP7
Proline SCHEMBL15322392	0.80	ACE (0.32)	DPP7
Deaminohydroxyvaline SCHEMBL15322556	0.78	TET2 (0.46)	—
Proline SCHEMBL15322641	0.75	PRCP (0.39)	DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2836833-A1	PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18	Wayne State University (US)	2015-02-18	—	—	EP	disclosed
WO-2013155456-A1	PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18	WAYNE STATE UNIVERSITY (US)	2013-10-17	—	—	WO	disclosed