Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL15323788 | 0.85 | SLC7A5 (0.51) | ANPEPRNPEPDNPEPSLC7A5ALPI | |
| Phenylalanine SCHEMBL15323790 | 0.85 | SLC7A5 (0.51) | ANPEPRNPEPDNPEPSLC7A5ALPI | |
| Phenylalanine SCHEMBL15323513 | 0.84 | ANPEP (0.35) | ANPEPRNPEPDNPEPSLC7A5ALPI | |
| SCHEMBL9632995 | 0.83 | MEN1 (0.58) | SLC7A5MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL9632999 | 0.83 | MEN1 (0.58) | SLC7A5MEN1KMT2ACYP1A2HRH1 | |
| Leucine SCHEMBL15323857 | 0.83 | ANPEP (0.36) | ANPEPRNPEPDNPEPSLC7A5ALPI | |
| Leucine SCHEMBL17165661 | 0.82 | MEN1 (0.51) | SLC7A5MEN1KMT2ACYP1A2HRH1 | |
| Levocarnitine Propionate SCHEMBL4201263 | 0.82 | MEN1 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Propionyl-Carnitine SCHEMBL4201261 | 0.82 | MEN1 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| Propionyl-Carnitine SCHEMBL27472872 | 0.82 | MEN1 (0.61) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |