SCHEMBL1532392

SCHEMBL1532392

C[C]1CCCCCCC1C

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.54
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
GAA P10253 2/20 0.33
HRH2 P25021 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
PKM P14618 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114252 1.00 KMT2A (0.54) KMT2ACA1CA2CA4GAA
SCHEMBL21114295 1.00 KMT2A (0.54) KMT2ACA1CA2CA4GAA
SCHEMBL21114291 1.00 KMT2A (0.54) KMT2ACA1CA2CA4GAA
SCHEMBL10866902 1.00 KMT2A (0.54) KMT2ACA1CA2CA4GAA
SCHEMBL258383 1.00
SCHEMBL4468 0.97
SCHEMBL5278 0.88
SCHEMBL7557757 0.76 KMT2A (0.52) KMT2ACA1CA2CA4GAA
SCHEMBL1051638 0.76 KMT2A (0.52) KMT2ACA1CA2CA4GAA
SCHEMBL1051636 0.76 KMT2A (0.52) KMT2ACA1CA2CA4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO claimed
EP-4385984-A1 PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
EP-4385979-A1 MULTICYCLIC INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP claimed
CN-109942549-A A kind of low alkalinity polymerized hindered amine light stabilizer and preparation method thereof 北京天罡助剂有限责任公司 2019-06-28 CN claimed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 WO disclosed
EP-4385984-A1 PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP disclosed
EP-4385979-A1 MULTICYCLIC INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2024-06-19 EP disclosed
EP-3845580-B1 ALIPHATIC POLYESTER WITH HIGH ELONGATION CHANG CHUN PLASTICS CO LTD (TW) 2023-10-25 EP disclosed
CN-111830291-B Test connector suitable for extremely low temperature 株式会社ISC 2023-04-07 CN disclosed
US-20230057670-A1 NON-AQUEOUS ELECTROLYTE AND ENERGY DEVICE USING SAID NON-AQUEOUS ELECTROLYTE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
EP-4123781-A1 NON-AQUEOUS ELECTROLYTE AND ENERGY DEVICE USING SAID NON-AQUEOUS ELECTROLYTE Mitsubishi Chemical Corporation (JP) 2023-01-25 EP disclosed
CN-115315839-A Nonaqueous electrolyte solution and energy device using same 三菱化学株式会社 2022-11-08 CN disclosed
US-5256827-A Process for making 3-hydroxypropanal and 1,3-propanediol SHELL OIL COMPANY (US) 1993-10-26 US disclosed
US-5155268-A Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides THE UPJOHN COMPANY (US) 1992-10-13 US disclosed
EP-0164865-B1 N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE THE UPJOHN COMPANY (US) 1988-12-21 EP disclosed
US-4618722-A Preparation of organic sulfides PHILLIPS PETROLEUM COMPANY (US) 1986-10-21 US disclosed
EP-0104146-B1 COLOUR-PHOTOGRAPHIC RECORDING MATERIAL CIBA-GEIGY AG (CH) 1986-07-30 EP disclosed
EP-0164865-A1 N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use THE UPJOHN COMPANY (US) 1985-12-18 EP disclosed
US-4465757-A PYRIDINE STABILIZERS CIBA-GEIGY A.G. (CH) 1984-08-14 US disclosed
EP-0104146-A1 Colour-photographic recording material CIBA-GEIGY AG (CH) 1984-03-28 EP disclosed