Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888638 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL15533143 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL15322412 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL15776983 | 0.97 | — | — | |
| SCHEMBL17978235 | 0.90 | — | — | |
| SCHEMBL17978256 | 0.88 | — | — | |
| SCHEMBL2250515 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL17978336 | 0.87 | — | — | |
| SCHEMBL20143909 | 0.86 | — | — | |
| SCHEMBL15205714 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153492-A2 | PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-10-17 | — | — | WO | claimed |
| US-9969721-B2 | Process for the preparation of vilazodone hydrochloride and its amorphous form | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2018-05-15 | — | — | US | disclosed |
| US-9493443-B2 | Process for the preparation of vilazodone hydrochloride and its amorphous form | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2016-11-15 | — | — | US | disclosed |
| US-20150239871-A1 | PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2015-08-27 | — | — | US | disclosed |
| US-20150087835-A1 | PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2015-03-26 | — | — | US | disclosed |
| WO-2013153492-A2 | PROCESS FOR THE PREPARATION OF VILAZODONE HYDROCHLORIDE AND ITS AMORPHOUS FORM | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-10-17 | — | — | WO | disclosed |