⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539502 | 1.00 | — | — | |
| SCHEMBL153253 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL154419 | 0.97 | DPP4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL150794 | 0.97 | DPP4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL150793 | 0.97 | DPP4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL16448116 | 0.97 | DPP4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL16448114 | 0.97 | DPP4 (0.31) | — | |
| SCHEMBL10052671 | 0.92 | — | — | |
| SCHEMBL6272620 | 0.89 | DPP4 (0.32) | — | |
| SCHEMBL30363451 | 0.89 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031974-A | Ink for ink jet printing and electroluminescent device | 广东聚华印刷显示技术有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-109748903-B | Preparation method of pyrifazimine | 北京协和制药二厂 | 2021-08-10 | — | — | CN | claimed |
| CN-107474051-A | Pharmaceutical composition, its solid form and their purposes of dihydro pyrazine and pyrazine compound | 西格诺药品有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-105407892-A | Pharmaceutical compositions of 7- (6- (2-hydroxypropan-2-yl) pyridin-3-yl) -1- ((trans) -4-methoxycyclohexyl) -3, 4-dihydropyrazino [2,3-B ] pyrazin-2 (1H) -one, solid forms thereof, and methods of their use | SIGNAL PHARM LLC | 2016-03-16 | — | — | CN | claimed |
| US-8916599-B2 | 1H-benz imidazole-5-carboxamides as anti-inflammatory agents | OREXO AB (SE) | 2014-12-23 | — | — | US | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| US-20260138990-A1 | TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4724430-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | Flagship Pioneering Innovations VI, LLC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-4702026-A1 | TRICYCLIC FUSED IMIDAZOLE COMPOUNDS AS CD38 MODULATORS AND USES THEREOF | Aeovian Pharmaceuticals, Inc. (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20260042774-A1 | CAMPTOTHECIN-7-ETHYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | HANGZHOU ADCORIS BIOPHARMA CO LTD (CN) | 2026-02-12 | — | — | US | disclosed |
| US-12514858-B2 | CD38 inhibitors | Astellas Engineered Small Molecules US, Incorporated (US) | 2026-01-06 | — | — | US | disclosed |
| US-20250320217-A1 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS | SUMITOMO PHARMA AMERICA INC (US) | 2025-10-16 | — | — | US | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |
| US-20060287344-A1 | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith | PHARMACOPEIA, LLC | 2006-12-21 | — | — | US | disclosed |
| WO-2006076595-A1 | HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2005090305-A1 | 5-AMINO-4-HYDROXY-7-(1H-INDOLMETHYL)-8-METHYLNONAMIDE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | SPEEDEL EXPERIMENTA AG (CH) | 2005-09-29 | — | — | WO | disclosed |
| EP-0296748-B1 | CYCLOALKYLAMIDES OF (8BETA)-1-ALKYL-6-(SUBSTITUTED) ERGOLINES | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4931447-A | BLOCKING 5HT2 RECEPTORS IN MAMMALS HAVING AN EXCESS OF SEROTONIN; HYPOTENSIVE AGENTS, ANTIDEPRESSANTS | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0296748-A1 | Cycloalkylamides of (8Beta)-1-alkyl-6-(substituted) ergolines | ELI LILLY AND COMPANY (US) | 1988-12-28 | — | — | EP | disclosed |