SCHEMBL15325919

SCHEMBL15325919

C[C@@H]1CCCC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12647014 1.00
SCHEMBL15683009 1.00
SCHEMBL765468 0.92
SCHEMBL15108355 0.92
SCHEMBL15683007 0.92
SCHEMBL8051162 0.89 MAPT (0.30)
SCHEMBL24588940 0.78
SCHEMBL16938868 0.78
SCHEMBL696215 0.78
SCHEMBL16386242 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007188-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2023-02-02 WO disclosed
US-20200075870-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-03-05 US disclosed
WO-2019070742-A1 APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK 1) INHIBITOR COMPOUNDS SIDECAR THERAPEUTICS, INC. (US) 2019-04-11 WO disclosed
US-20160355511-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2016-12-08 US disclosed
US-20160355511-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2016-12-08 US disclosed
US-9309221-B2 1-substituted indazole derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-04-12 US disclosed
US-9309221-B2 1-substituted indazole derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-04-12 US disclosed
US-9051295-B2 1-substituted indazole derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2015-06-09 US disclosed
US-9051295-B2 1-substituted indazole derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2015-06-09 US disclosed
EP-2837623-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Dainippon Pharma Co., Ltd. (JP) 2015-02-18 EP disclosed
US-20150031681-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2015-01-29 US disclosed
US-20150031681-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2015-01-29 US disclosed
US-8765786-B2 1-substituted indazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2014-07-01 US disclosed
US-8765786-B2 1-substituted indazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2014-07-01 US disclosed
US-20140121244-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2014-05-01 US disclosed
US-20140121244-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2014-05-01 US disclosed
US-20140121243-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2014-05-01 US disclosed
US-20140121243-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2014-05-01 US disclosed
WO-2013154109-A1 NOVEL 1-SUBSTITUTED INDAZOLE DERIVATIVE 大日本住友製薬株式会社 (JP) 2013-10-17 WO disclosed