Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 16/20 | 0.66 |
| ▸ | BCL2 | P10415 | 14/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951313 | 0.93 | BCL2L1 (0.61) | BCL2L1BCL2 | |
| SCHEMBL9951668 | 0.89 | BCL2L1 (0.65) | BCL2L1BCL2 | |
| SCHEMBL9951249 | 0.88 | BCL2L1 (0.62) | BCL2L1BCL2 | |
| SCHEMBL9951155 | 0.86 | BCL2L1 (0.65) | BCL2L1BCL2 | |
| SCHEMBL9951151 | 0.83 | BCL2L1 (0.60) | BCL2L1BCL2 | |
| SCHEMBL9951183 | 0.83 | BCL2L1 (0.57) | BCL2L1BCL2 | |
| SCHEMBL9951150 | 0.82 | BCL2L1 (0.57) | BCL2L1BCL2 | |
| SCHEMBL9951406 | 0.81 | BCL2L1 (0.55) | BCL2L1BCL2 | |
| SCHEMBL9950617 | 0.81 | BCL2L1 (0.56) | BCL2L1BCL2 | |
| SCHEMBL9951770 | 0.81 | BCL2 (0.84) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475661-B1 | SULFONAMIDES AS INHIBITORS OF BCL-2 FAMILY PROTEINS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2013-10-23 | — | — | EP | disclosed |