Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872939 | 1.00 | ATM (0.45) | ATMSLC5A2SLC5A1EPHX2TYMP | |
| SCHEMBL153288 | 1.00 | ATM (0.45) | ATMSLC5A2SLC5A1EPHX2TYMP | |
| SCHEMBL27856161 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL21597963 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL151973 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL151972 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL14058431 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL21597962 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL154837 | 0.90 | MEN1 (0.41) | SLC5A2SLC5A1EPHX2TYMPMEN1 | |
| SCHEMBL153287 | 0.89 | HK1 (0.37) | SLC5A2SLC5A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |