SCHEMBL15330307

SCHEMBL15330307

N[C@@H](CO)c1ccc(C=O)nc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 1/20 0.34
CCR1 P32246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15329718 1.00 KCNJ1 (0.34) KCNJ1CCR1
SCHEMBL15331456 0.84 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL15331646 0.84 KCNJ1 (0.35) KCNJ1CCR1
SCHEMBL15331982 0.83 SLC6A4 (0.41) KCNJ1CCR1
SCHEMBL2555343 0.83 SLC6A4 (0.41) KCNJ1CCR1
SCHEMBL2561270 0.80 IRAK4 (0.35) KCNJ1
SCHEMBL15332598 0.80 IRAK4 (0.35) KCNJ1
SCHEMBL29955865 0.79 KCNJ1 (0.32) KCNJ1
SCHEMBL29952432 0.79 KCNJ1 (0.32) KCNJ1
SCHEMBL2560539 0.78 SLC2A1 (0.42) KCNJ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed