Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933371 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTPOLBALDH1A1MEN1 | |
| SCHEMBL20590320 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2HTTPOLBALDH1A1MEN1 | |
| SCHEMBL8264250 | 0.80 | MEN1 (0.66) | SMN1; SMN2HTTTSHRPOLBALDH1A1 | |
| SCHEMBL13908688 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTPOLBALDH1A1MEN1 | |
| SCHEMBL23865499 | 0.75 | SMN1; SMN2 (0.70) | SMN1; SMN2HTTPOLBALDH1A1MEN1 | |
| SCHEMBL24480014 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2HTTTSHRPOLBALDH1A1 | |
| SCHEMBL29950814 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2HTTTSHRPOLBALDH1A1 | |
| SCHEMBL1520360 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTPOLBALDH1A1MEN1 | |
| SCHEMBL17679199 | 0.73 | TDP1 (0.64) | SMN1; SMN2HTTTSHRALDH1A1MEN1 | |
| SCHEMBL29956465 | 0.73 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTTSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |