Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552261 | 0.90 | GRK6 (0.43) | ALDH1A1TDP1GRK6KDM4EFFAR1 | |
| SCHEMBL21764082 | 0.86 | GRK6 (0.37) | ALDH1A1TDP1GRK6KDM4EFFAR1 | |
| SCHEMBL17213015 | 0.86 | GRK6 (0.46) | ALDH1A1TDP1GRK6FFAR1KMT2A | |
| SCHEMBL14907846 | 0.85 | MAPT (0.48) | ALDH1A1TDP1GRK6KDM4EFFAR1 | |
| SCHEMBL6405045 | 0.84 | GRK6 (0.60) | ALDH1A1TDP1GRK6KDM4EKMT2A | |
| SCHEMBL21763898 | 0.81 | STK17B (0.48) | ALDH1A1TDP1GRK6KDM4EFFAR1 | |
| SCHEMBL14907821 | 0.81 | GRK6 (0.62) | ALDH1A1TDP1GRK6KDM4EKMT2A | |
| SCHEMBL14907851 | 0.81 | GRK6 (0.60) | ALDH1A1TDP1GRK6KDM4EKMT2A | |
| SCHEMBL14907836 | 0.81 | APEX1 (0.51) | ALDH1A1TDP1GRK6KDM4EKMT2A | |
| SCHEMBL16171157 | 0.81 | GRK6 (0.50) | ALDH1A1TDP1GRK6KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |