Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15328312 | 0.88 | P2RY2 (0.34) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328213 | 0.88 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328215 | 0.88 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328610 | 0.87 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328614 | 0.87 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL17074557 | 0.86 | P2RY2 (0.33) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328386 | 0.86 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL17074554 | 0.86 | P2RY2 (0.33) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15328383 | 0.86 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1CSNK2A3P2RY2 | |
| SCHEMBL15344127 | 0.83 | P2RY2 (0.43) | P2RY2KMT2AFPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | CSNK2A2 2005/4885CSNK2B 1944/4885CSNK2A1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.