Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545712 | 0.93 | CLCN2 (0.46) | CLCN2HMGB1FOLH1BIDMCL1 | |
| Ammonia Solution, Strong SCHEMBL7718320 | 0.91 | CLCN2 (0.45) | CLCN2HMGB1FOLH1BIDMCL1 | |
| Ammonia Solution, Strong SCHEMBL7718324 | 0.91 | CLCN2 (0.45) | CLCN2HMGB1FOLH1BIDMCL1 | |
| SCHEMBL13571301 | 0.89 | BID (0.50) | CLCN2HMGB1FOLH1GABRA1GABRB2 | |
| SCHEMBL15344588 | 0.89 | CLCN2 (0.50) | CLCN2HMGB1FOLH1GABRA1GABRB2 | |
| SCHEMBL578127 | 0.88 | CLCN2 (0.56) | CLCN2HMGB1FOLH1MRGPRX4GABRA1 | |
| SCHEMBL15344563 | 0.88 | BID (0.45) | CLCN2HMGB1FOLH1GABRA1GABRB2 | |
| Ammonia Solution, Strong SCHEMBL29557133 | 0.86 | CLCN2 (0.54) | CLCN2HMGB1FOLH1MRGPRX4GABRA1 | |
| SCHEMBL12475346 | 0.85 | PRKCI (0.42) | CLCN2GABRA1GABRB2HTTALDH1A1 | |
| SCHEMBL28818542 | 0.85 | TSHR (0.47) | CLCN2HMGB1FOLH1HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |