Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 19/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.62 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966848 | 0.84 | FGFR2 (0.61) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL20808457 | 0.80 | FGFR2 (0.93) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15966847 | 0.80 | FGFR2 (0.93) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL16241633 | 0.80 | FGFR2 (0.93) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15966846 | 0.80 | FGFR2 (0.93) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15967400 | 0.79 | FGFR2 (0.71) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345802 | 0.79 | FGFR2 (1.00) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345746 | 0.79 | FGFR2 (1.00) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345747 | 0.79 | FGFR2 (1.00) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345801 | 0.79 | FGFR2 (1.00) | FGFR2FGFR1FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657233-A1 | 3,5-DISUBSTITUTED ALKYNYLBENZENE COMPOUND AND SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-10-30 | — | — | EP | disclosed |