SCHEMBL15345859

SCHEMBL15345859

Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc([O])cc3C)cc12

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008680 0.92 TLR7 (0.73) TLR7
SCHEMBL18752998 0.87 TLR7 (0.67) TLR7
SCHEMBL1061517 0.87 TLR7 (0.70) TLR7
SCHEMBL1061351 0.87 TLR7 (0.66) TLR7
SCHEMBL1062444 0.87 TLR7 (0.67) TLR7
SCHEMBL18726329 0.87 TLR7 (0.67) TLR7
SCHEMBL1055566 0.86 TLR7 (0.69) TLR7
SCHEMBL13447192 0.86 TLR7 (0.66) TLR7
SCHEMBL1062056 0.86 TLR7 (0.68) TLR7
SCHEMBL1062942 0.86 TLR7 (0.68) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459216-B1 IMMUNOGENIC COMPOSITIONS INCLUDING TLR ACTIVITY MODULATORS NOVARTIS AG (CH) 2013-10-30 EP disclosed