SCHEMBL15364398

SCHEMBL15364398

Nc1ccc(OC(=O)/C=C/c2cccc(N)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.61
CYP19A1 P11511 4/20 0.54
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.49
KDM4E B2RXH2 1/20 0.49
GAA P10253 1/20 0.49
MAOB P27338 4/20 0.47
MAOA P21397 3/20 0.47
CYP3A4 P08684 1/20 0.44
CYP1B1 Q16678 1/20 0.44
HTR1A P08908 1/20 0.43
PKM P14618 1/20 0.43
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
GFER P55789 1/20 0.42
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15363574 0.94 KMT2A (0.55) NPSR1CYP19A1KMT2AMEN1KDM4E
SCHEMBL30775462 0.94 KMT2A (0.55) NPSR1CYP19A1KMT2AMEN1KDM4E
SCHEMBL15364375 0.89 NPSR1 (0.63) NPSR1CYP19A1KMT2AMEN1KDM4E
SCHEMBL6911782 0.89 NPSR1 (0.63) NPSR1CYP19A1KMT2AMEN1KDM4E
SCHEMBL15364342 0.88 KMT2A (0.57) NPSR1CYP19A1KMT2AMEN1KDM4E
SCHEMBL27758580 0.87 MAOB (0.58) NPSR1KMT2AMEN1KDM4EGAA
SCHEMBL27758521 0.87 MAOB (0.58) NPSR1KMT2AMEN1KDM4EGAA
SCHEMBL5089442 0.85 KMT2A (0.71) CYP19A1KMT2AMEN1KDM4EMAOB
SCHEMBL15364371 0.84 CYP19A1 (0.50) NPSR1CYP19A1KMT2AMEN1CYP3A4
SCHEMBL15363576 0.83 KMT2A (0.62) CYP19A1KMT2AMEN1KDM4ECYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104395282-A Diamine, polymer, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element NISSAN CHEMICAL IND LTD 2015-03-04 CN disclosed
WO-2013161984-A1 DIAMINE, POLYMER, LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2013-10-31 WO disclosed