SCHEMBL1536443

SCHEMBL1536443

C/C(=C/C(=O)O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.60
NR4A1 P22736 1/20 0.60
NR4A3 Q92570 1/20 0.60
DEGS1 O15121 1/20 0.53
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
TBXAS1 P24557 2/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NFE2L2 Q16236 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
HTT P42858 1/20 0.46
CA12 O43570 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL691911 1.00 NR4A2 (0.60) NR4A2NR4A1NR4A3DEGS1CES2
SCHEMBL582234 1.00 NR4A2 (0.60) NR4A2NR4A1NR4A3DEGS1CES2
Ammonia Solution, Strong SCHEMBL6327043 0.98 NR4A2 (0.58) NR4A2NR4A1NR4A3DEGS1CES2
Hydrochloric Acid SCHEMBL11760666 0.98 NR4A2 (0.58) NR4A2NR4A1NR4A3DEGS1CES2
Acetic Acid SCHEMBL6897120 0.98 NR4A2 (0.58) NR4A2NR4A1NR4A3DEGS1CES2
SCHEMBL27719682 0.98 NR4A2 (0.58) NR4A2NR4A1NR4A3DEGS1CES2
SCHEMBL11243246 0.87 SMN1; SMN2 (0.61) NR4A2NR4A1NR4A3TBXAS1SMN1; SMN2
SCHEMBL11243242 0.87 SMN1; SMN2 (0.61) NR4A2NR4A1NR4A3TBXAS1SMN1; SMN2
SCHEMBL566351 0.86 DEGS1 (0.53) NR4A2NR4A1NR4A3DEGS1CES2
SCHEMBL566350 0.86 DEGS1 (0.53) NR4A2NR4A1NR4A3DEGS1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110229152-B 2-bit disubstituted indoline-3-ketone compound and asymmetric synthesis method thereof 中国药科大学 2020-06-23 CN claimed
US-20250188201-A1 CATALYST FOR PHOTOCATALYTIC POLYMERIZATION REACTION, AND APPLICATION THEREOF BEIJING INSTITUTE OF FASHION TECHNOLOGY (CN) 2025-06-12 US disclosed
EP-4353759-A1 PRODUCTION METHOD FOR AQUEOUS FLUORINE-CONTAINING ELASTOMER DISPERSION, COMPOSITION, AND AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2024-04-17 EP disclosed
CN-117529511-A Method for producing aqueous dispersion of fluoroelastomer, composition, and aqueous dispersion 大金工业株式会社 2024-02-06 CN disclosed
CN-116854744-A Synthesis and application of chiral spiro [ chromane-4, 1' -indan ] bidentate ligand iridium complex 南开大学 2023-10-10 CN disclosed
CN-116813823-A Supported catalyst, preparation method thereof and application thereof in photocatalytic polymerization 北京服装学院 2023-09-29 CN disclosed
CN-116770330-A Electrochemical preparation method of (E) -alpha, beta-unsaturated silane compound 华南理工大学 2023-09-19 CN disclosed
US-20230192924-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION DAIKIN INDUSTRIES, LTD. (JP) 2023-06-22 US disclosed
EP-4194474-A1 METHOD FOR PRODUCING AQUEOUS DISPERSION OF FLUORINE-CONTAINING ELASTOMER Daikin Industries, Ltd. (JP) 2023-06-14 EP disclosed
EP-4186932-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION AND FLUORINE-CONTAINING ELASTOMER AQUEOUS DISPERSION Daikin Industries, Ltd. (JP) 2023-05-31 EP disclosed
WO-2002026696-A1 CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS PROLIFIX LIMITED (GB) 2002-04-04 WO disclosed
WO-2001036417-A1 NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2001-05-25 WO disclosed
US-6004988-A Carboxylic acid derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
US-5484543-A Amide containing friction modifier for use in power transmission fluids EXXON CHEMICAL PATENTS INC. (US) 1996-01-16 US disclosed
US-5395539-A Friction resistance for lubricants EXXON CHEMICAL PATENTS INC. (US) 1995-03-07 US disclosed
EP-0394422-A1 AMIDE CONTAINING FRICTION MODIFIER FOR USE IN POWER TRANSMISSION FLUIDS. EXXON CHEMICAL CO (US) 1990-10-31 EP disclosed
WO-1990004625-A2 AMIDE CONTAINING FRICTION MODIFIER FOR USE IN POWER TRANSMISSION FLUIDS EXXON CHEMICAL COMPANY (US) 1990-05-03 WO disclosed
US-4588833-A CARBON MONOXIDE, ALCOHOL OR AMINE, ACID, UNSATURATED AMIDE, COBALTCOMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
EP-0010918-B1 ANTIFREEZE AGENTS Smiths Industries Public Limited Company (GB) 1983-04-13 EP disclosed
EP-0010918-A1 Antifreeze agents Smiths Industries Public Limited Company (GB) 1980-05-14 EP disclosed