Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 6/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025807 | 0.90 | CARM1 (0.50) | CARM1SMOPRMT5WDR77 | |
| SCHEMBL303681 | 0.90 | CARM1 (0.50) | CARM1SMOPRMT5WDR77 | |
| SCHEMBL304344 | 0.90 | CARM1 (0.50) | CARM1SMOPRMT5WDR77 | |
| SCHEMBL30090666 | 0.90 | CARM1 (0.50) | CARM1SMOPRMT5WDR77 | |
| SCHEMBL2029850 | 0.89 | SMO (0.41) | CARM1SMO | |
| SCHEMBL302292 | 0.89 | SMO (0.43) | CARM1SMO | |
| SCHEMBL302505 | 0.87 | SMO (0.43) | CARM1SMO | |
| SCHEMBL1923378 | 0.86 | SMO (0.43) | CARM1SMO | |
| SCHEMBL1921989 | 0.86 | SMO (0.42) | SMO | |
| SCHEMBL1922090 | 0.86 | SMO (0.42) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216964-B2 | Hedgehog pathway modulators | NOVARTIS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-20130296333-A1 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296333-A1 | HEDGEHOG PATHWAY MODULATORS | GLI1, SHH, SMO | CARM1 473/4885SMO 3/4885PRMT5 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.