Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359161 | 0.98 | TDP1 (0.59) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| SCHEMBL5399 | 0.98 | TDP1 (0.59) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| SCHEMBL28652434 | 0.95 | TDP1 (0.57) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| Bromide SCHEMBL10432264 | 0.95 | TDP1 (0.57) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7206595 | 0.95 | TDP1 (0.57) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3713895 | 0.95 | TDP1 (0.57) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| Bromide SCHEMBL6955674 | 0.95 | TDP1 (0.57) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| Methylamine SCHEMBL28557648 | 0.93 | TDP1 (0.55) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| SCHEMBL30395666 | 0.90 | TDP1 (0.52) | TDP1GRM5HTTCYP11B1CYP11B2 | |
| SCHEMBL15639423 | 0.90 | TDP1 (0.52) | TDP1GRM5HTTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |
| WO-2013167586-A1 | IONIC LIQUIDS, METHOD FOR MANUFACTURING THEREOF, AND ELECTROCHEMICAL DEVICES COMPRISING THE SAME | SOLVAY SA (BE) | 2013-11-14 | — | — | WO | disclosed |
| EP-2662359-A1 | Ionic Liquids, Method for manufacturing thereof, and Electrochemical Devices Comprising the Same | SOLVAY SA (BE) | 2013-11-13 | — | — | EP | disclosed |