Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390822 | 0.87 | ITGAL (0.63) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL15375594 | 0.86 | ITGAL (0.61) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2392873 | 0.85 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12802610 | 0.85 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2392862 | 0.85 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12802612 | 0.85 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2388923 | 0.81 | ITGAL (0.61) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2393042 | 0.79 | ITGAL (0.75) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2393045 | 0.79 | ITGAL (0.75) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2394309 | 0.78 | ITGAL (0.66) | ITGALITGB2ICAM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |