SCHEMBL153805

SCHEMBL153805

[C]1CSC=CS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22954 0.55
SCHEMBL3060 0.55
SCHEMBL22569 0.52
SCHEMBL5229330 0.52
SCHEMBL11135939 0.49
SCHEMBL452580 0.39
SCHEMBL29462554 0.36
SCHEMBL29464072 0.36
SCHEMBL561897 0.35
SCHEMBL30943803 0.30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770079-B1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2003-02-12 EP claimed
EP-0686156-B1 PYRAZOLITRIAZINES WITH INTERLEUKIN-1 AND TUMOUR NECROSIS FACTOR INHIBITORY ACTIVITY FUJISAWA PHARMACEUTICAL CO (JP) 2002-07-17 EP claimed
US-5739130-A TREATING SYSTEMIC LUPUS ERYTHEMATOSIS, MELANOMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-04-14 US claimed
US-5583135-A TREATING SYSTEMIC LUPUS ERYTHEMATOSIS OR MELANOMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-12-10 US claimed
US-5322842-A Tricyclic benzodiazepine derivates, their preparation, and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-06-21 US claimed
US-5248679-A Tricyclic compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-09-28 US claimed
US-5217952-A Analgesics, antihistamine FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-06-08 US claimed
US-20240239805-A1 AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES UNIVERSITY OF KANSAS 2024-07-18 US disclosed
EP-4398911-A2 INK4 TUMOR SUPPRESSOR PROTEINS MEDIATE RESISTANCE TO CDK4/6 KINASE INHIBITORS Memorial Sloan Kettering Cancer Center (US) 2024-07-17 EP disclosed
CN-118344338-A Substituted 4-aminoisoindoline-1, 3-dione compounds and their use for the treatment of lymphomas 细胞基因公司 2024-07-16 CN disclosed
CN-115210273-B Process for controlling the formation of ziegler-natta procatalyst particles and use for olefin polymerization 布拉斯科美国公司 2024-07-12 CN disclosed
WO-2024140935-A1 B7H3 ANTIBODY DRUG CONJUGATES BEIGENE, LTD. (KY) 2024-07-04 WO disclosed
WO-2024140690-A1 INTERMEDIATES OF SONROTOCLAX AND THE METHOD OF PREPARING THE SAME BEIGENE (SUZHOU) CO., LTD. (CN) 2024-07-04 WO disclosed
US-4288436-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-09-08 US disclosed
EP-0029557-A2 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-03 EP disclosed
US-4264597-A FUNGICIDES FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN 1981-04-28 US disclosed
EP-0025199-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-03-18 EP disclosed
US-4234724-A OXADETHIACEPHEMCARBOXYLIC ACIDS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-11-18 US disclosed
EP-0017138-A2 Analogous compounds of cephalosporins, processes for their preparation, and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-10-15 EP disclosed
EP-0009548-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-16 EP disclosed